UPDATE 12/7/17 @ 4:40 PM:
Detectives have identified both the car and the man in the dark-colored jacket.  Detectives are still looking for the identity of the man in the light-colored jacket (please see attached photo).

Update:
Detectives are seeking two people of interest in this investigation.

The adult males (see attached photos) were seen inside the Holiday at the intersection of 68th Avenue and Lake Otis Parkway before the shooting. Also, during this time, an older model white Cadillac sedan (see attached photo) was parked at the Holiday. The male wearing the dark jacket was driving the vehicle. The male wearing fur hooded jacket was not in the vehicle and left on foot.
 
Detectives believe these men have information to solve this crime.
 
Anyone with information about these men, the white Cadillac and/or this investigation is asked to call Police Dispatch at 786-8900 (press “0” for an operator).  To remain anonymous you may contact Crime Stoppers at 561-STOP or online at www.anchoragecrimestoppers.com.
 
Update 12/4/17 @ 12:30 p.m.:
On 12/3/17 at 10:45 p.m., Dispatch received a report of shots fired at the intersection of 68th Avenue and Lake Otis Parkway.
 
The preliminary investigation found that there was an altercation between the victim and the suspect near the intersection. The victim, 26-year-old Joshua Statham, died at the hospital from his injury.  His death is being investigated as a homicide.  This is believed to be an isolated event.
 
Original on 12/3/17:
APD conducting a shooting investigation at 68th and O'Brien. One adult male was shot and transferred to a local hospital with life threatening injuries.  There is no suspect information to release. 
 
Please avoid the intersection as APD occupies the area. 
 
APD Case: 17-49673